Influenza Articles and Studies

See ACOG's commentary in Obstetrics & Gynecology in response to an article in Vaccine indicating a possible safety signal for influenza vaccination during pregnancy.

Dr. Haywood Brown, president of the American College of Obstetricians and Gynecologists (ACOG), gave a statement on the safety of the influenza vaccine during pregnancy (9/13/17).

  • View ACOG's Committee Opinion: Influenza Vaccination During Pregnancy here
  • View ACOG's Influenza Immunization during Pregnancy Toolkit here

CDC released a new HAN, Seasonal Influenza A(H3N2) Activity and Antiviral Treatment of Patients with Influenza (12/27/17) to remind clinicians that influenza should be high on their list of possible diagnoses for ill patients because influenza activity is increasing nationwide, and advise clinicians that all hospitalized patients and all high-risk patients (either hospitalized or outpatient) with suspected influenza should be treated as soon as possible with a neuraminidase inhibitor antiviral. While antiviral drugs work best when treatment is started within 2 days of illness onset, clinical benefit has been observed even when treatment is initiated later. 

CDC released a Flu Vaccination & Possible Safety Signal Fact Sheet for Health Care Providers. 

National Center for Immunization & Respiratory Disease released slides on Vaccinating pregnant women: New data and new Healthy People goal (5/11/17)

CDC's Morbidity and Mortality Weekly Report (MMWR)

Influenza Activity - United States, September 30 - December 1, 2018 (December 2018)

Influenza and Tdap Vaccination Coverage Among Pregnant Women - United States, April 2018 (September 2018)

Influenza Vaccination Coverage Among Health Care Personnel - United States, 2017-18 Influenza Season (September 2018)

Prevention and Control of Seasonal Influenza with Vaccines: Recommendations of the Advisory Committee on Immunization Practices - United States, 2018-19 Influenza Season (August 2018)

Update: Influenza Activity in the United States During the 2017-18 Season and Composition of the 2018-2019 Influenza Vaccine (June 2018)

Update: ACIP Recommendations for the Use of Quadrivalent Live Attenuated Influenza Vaccine (LAIV4) - United States, 2018-19 Influenza Season (June 2018)

Estimated Influenza Illnesses, Medical visits, and Hospitalizations Averted by Vaccination in the United States (April 2018)

Influenza Vaccination Coverage Among Pregnant Women - United States, 2016-17 Influenza Season (9/29/17)

Visit the CDC website for additional MMWRs. 

 

Influenza Vaccination during Pregnancy

2009 H1N1 Influenza and Pregnancy- 5 years later, by Sonja A. Rasmussen, M.D., and Denise J. Jamieson, M.D., M.P.H., a review of the importance of flu vaccine in pregnancy has been published by the New England Journal of Medicine.

Broughton D, Beigi R, Switzer G, Raker C, Anderson B. Obstetric Health Care Workers’ Attitudes and Beliefs Regarding Influenza Vaccination in Pregnancy. Obstetrics & Gynecology. November 2009; 114 (5): 981-987.

Callaghan W, Creanga A, Jamieson D. Pregnancy-Related Mortality Resulting From Influenza in the United States During the 2009–2010 Pandemic. Obstetrics & Gynecology. September 2015;126 (3):486–90.

Poster Presentation from ID week 2015: Maggio L, Has P, Hughes BL. Improving Obstetric Health Care Providers’ Attitude and Beliefs Regarding Influenza Vaccination in Pregnancy.

Duration of Infant Protection Againgst Influenza Illness Conferred by Maternal Immunization: Secondary Analysis of a Randomized Clinical Trial. Nunes MC, Cutland CL, Jones S, et al. Duration of Infant Protection Against Influenza Illness Conferred by Maternal Immunization: Secondary Analysis of a Randomized Clinical Trial. JAMA Pediatr.Published online July 05, 2016. doi:10.1001/jamapediatrics.2016.0921.

Maternal immunisation with trivalent inactivated influenza vaccine for prevention of influenza in infants in Mali: a prospective, active-controlled, observer-blind, randomised phase 4 trial.
Milagritos D Tapia, Samba O Sow, Boubou Tamboura, Ibrahima Tégueté, Marcela F Pasetti, Mamoudou Kodio, Uma Onwuchekwa, Sharon M Tennant, William C Blackwelder, Flanon Coulibaly, Awa Traoré, Adama Mamby Keita, Fadima Cheick Haidara, Fatoumata Diallo, Moussa Doumbia, Doh Sanogo, Ellen DeMatt, Nicholas H Schluterman, Andrea Buchwald, Karen L Kotloff, Wilbur H Chen, Evan W Orenstein, Lauren A V Orenstein, Julie Villanueva, Joseph Bresee, John Treanor, Myron M Levine, Maternal immunisation with trivalent inactivated influenza vaccine for prevention of influenza in infants in Mali: a prospective, active-controlled, observer-blind, randomised phase 4 trial, The Lancet Infectious Diseases, Available online 31 May 2016, ISSN 1473-3099, http://dx.doi.org/10.1016/S1473-3099(16)30054-8.

Kostinov MP, Cherdantsev AP, Pakhomov DC. Anti-Influenza Antibody Level in Mother-Infant Pairs Depending on Trimester of Vaccination of Pregnant Women Using Immunoadjuvant Vaccine. Vaccines & Vaccination. October 2, 2015. 6 (5): 297.

Polyzos K, Konstantelias A, Pitsa C, Falagas M. Maternal Influenza Vaccination and Risk for Congenital Malformations: A Systematic Review and Meta-analysisObstet Gynecol. November 2015. 126(5);1075-1084. 

Rasmussen SA, Watson AK, Kennedy ED, Broder KR, Jamieson DJ. Vaccines and pregnancy: past, present, and futureSemin Fetal Neonatal Med. 2014 Jun;19(3):161-9. Epub 2013 Dec 17

 



 

 

 

Updated 6/6/18

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